Mastering the Epigenome Transforming Human Healthspan

Redefining Genetic Medicine

Tune Therapeutics was founded upon cutting-edge advances in the mechanics of gene regulation. Our ‘genetic tuning’ technology enables exquisite levels of control over gene activity – activating, silencing, and fine-tuning the output of specific genes to reverse cellular dysfunction and disease.

Expanding the Landscape

Tune’s proprietary genetic tuning platform, TEMPO, confers the ability to dial gene expression up or down without cutting or altering the DNA sequence in any way. This shifts and expands the practical scope of genetic medicine – from targeting rare, single-gene disorders to addressing common, chronic, and age-related diseases.

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Pursuing Lifelong Health

With its powerful, multiplex capacity, TEMPO has the intrinsic potential to:

Target the master controllers of cellular identity and function
Steer stem cells toward specific pathways
Replace cells lost to aging and disease
Mediate the repair of age-damaged tissues and organs
Reduce chronic inflammation and immune dysfunction
Reverse or reset patterns of gene dysregulation responsible for many or most chronic, late-onset diseases

We aim to bring gene, cell, and regenerative therapies into a new era of human medicine – to address the common and chronic diseases that are straining healthcare systems and limiting human healthspan on a global scale.