Scientist or Engineer, Process Technology Development
Location: Seattle, WA
Tune Therapeutics is a cutting-edge biotechnology company founded by world-class leaders in epigenome editing. At Tune, we strive to develop paradigm-changing cell and gene therapies that leverage epigenetic programming for the treatment of devastating diseases. We are building a highly skilled and dynamic team with expertise that spans drug discovery through commercialization. We are passionate about the science of epigenetic editing and its potential to transform patient care.
Tune Therapeutics is seeking a Scientist or Engineer to join the CMC Technology and Feasibility (CMCTF) team. We are looking for a critical thinker and team player to contribute to our team’s efforts to identify enabling technologies for use with our epi-editing TEMPO platform. In this role, you will be responsible for assessing, developing, and implementing cutting edge process technologies for use in iPSC expansion, maturation, and differentiation workflows. Come be a part of a high speed, low drag team!
As a Scientist or Engineer in the CMCTF group you will have the following technical responsibilities:
- Identify novel and established process technologies for use in discovery, clinical, and commercial enabling efforts
- Design feasibility studies comparing technologies to in-house gold standard protocols
- Develop and execute fit-for-purpose iPSC expansion, maturation, and differentiation processes
- Provide use case and guidance of selected technologies to program stakeholders and leadership
- Work with colleagues to maintain laboratory in good working order as well as uphold standards of safety
- Maintain laboratory notebooks and other documentation as need for regulatory filings
Education and Experience Required:
- PhD with 0-3 years or MS with 3-6 years or BS with degree with 6-10 years of experience
- Background in cell biology, Immunology, microbiology, bioengineering, or relevant biomedical sciences required
- Experience with iPSC cell culturing techniques and platforms (e.g., 2D culture and 3D bioreactors)
- Foundational knowledge of cell therapy process development: emphasis on iPSC
- Previous experience with CRISPR/Cas9 gene editing or epigenetic editing approaches is desired
- Experience with ex vivo culture media formulation and testing is desired
- Familiarity with design-of-experiment design is desired
- Familiarity with process characterization analytical methods, such as multi-color flow cytometry and cell-based functional assays is desired
- Experience with Electronic Laboratory Notebooks (ELN)
- Demonstrated collaboration skills working cross functionally and maintain strong stakeholder relationships
Explore Passionately. Innovate Boldly. Execute Selflessly. Come bring the song to life!
How to Apply:
Please send cover letter and resume to careers@tunetx.com with the job title in the subject line.
Tune Therapeutics is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Tune Therapeutics is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment.
